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SCIENCE BEHIND

We didn’t guess. We proved it.

Numin is built on a specific neuroscientific mechanism and validated in a peer-reviewed clinical trial. This page is everything we know, everything we tested, and everything we found.

Why your thinking degrades by mid-afternoon.

Every decision you make — from morning emails to afternoon meetings — produces glutamate in your lateral prefrontal cortex.

As glutamate accumulates, neural signalling becomes less efficient. The result: slower thinking, weaker focus, and worse decisions — not because you’re lazy, but because your brain chemistry has shifted.

Read the glutamate research

Double-blind. Placebo-controlled. Crossover. Published.

Study Design

Design:

Randomised, placebo-controlled, crossover

Participants:

Healthy adults under sustained cognitive load (13-hour protocol, 10 competitive matches)

Duration:

Two 13-hour sessions with 7-day washout between arms

Published:

Frontiers in Nutrition, 2025

Conducted:

Phoenix, AZ

"While the placebo group showed a statistically significant decline in cognitive efficiency after 4 hours, the Numin group maintained baseline performance until the end of the observation window."

Results

43% fewer decision errors

Under sustained cognitive load compared to placebo.

Performance held stable

Across a 13-hour session. Numin users maintained tactical execution from morning to evening.

Improved strategic communication

Strategic communication measured in real-time during competitive play.

Five ingredients. Each one does a specific job.

Standardised to 3% rosavins and 2% salidrosides. Rosavins support stress resilience; salidrosides protect against excitotoxic neural injury. Research in human cortical neurons shows significant protection against glutamate-induced cell death.

Ten times the potency of standard turmeric, engineered for bioavailability. Supports mood stability and reduces neural inflammation under load.

Neurotransmitter support. Supports working memory and cognitive flexibility when reserves deplete under stress.

Crosses the blood-brain barrier. Suppresses oxidative stress to preserve the signalling environment your decisions depend on.

Supports glucose uptake to the prefrontal cortex so your brain maintains its preferred fuel source during sustained work.

Made in the USA.
No shortcuts.

  • Non-GMO
  • Allergen free
  • Manufactured in a GMP-compliant
  • NSF-certified facility

The science is published. The product is proven. The rest is up to you.

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Numin 20 Pack

20 Servings, One Month Supply

$60/mo